| Description |
498 pages : illustrations ; 24 cm |
| Content |
text txt |
| Media |
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| Carrier |
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| Note |
Includes index. |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Thermodynamics -- Ideal Gases -- Real Gases -- Thermodynamics -- The First Law of Thermodynamics -- Enthalpy (Heat Content) and Heat Capacity -- Thermochemistry -- Heat Engine and the Carnot Cycle -- The Second Law of Thermodynamics and Entropy -- The Third Law of Thermodynamics -- Free Energy -- Free Energy Functions -- Fundamental Equations of Thermodynamics and Their Uses -- Free Energy of Formation and Standard Free Energy Change -- Free Energy and Chemical Equilibrium -- The Thermodynamics of Mixing -- Ionic Equilibrium -- Strong Acids and Strong Bases -- pH of the Solution of a Strong Acid or Strong Base -- Titration Curve of a Strong Base with a Strong Acid -- Monoprotic Weak Acids and Weak Bases -- pH of the Solution of a Monoprotic Weak Acid or Weak Base -- Titration Curve of a Weak Acid with a Strong Base -- pH of the Solution of Salts of Weak Acids or Weak Bases -- pH of the Solution of a Mixture of Conjugate Acids and Bases: Henderson-Hasselbalch Equation -- Buffer Solutions and Buffer Capacity -- Effect of Ionic Strength on Buffers -- Solubility of Weak Electrolytes and Ampholytes -- Polyprotic Weak Acids and Weak Bases -- pH of the Solution of a Diprotic Weak Acid, Weak Base, or Ampholyte -- pH of the Solution of a Triprotic Weak Acid, Weak Base, or Polyprotic Amino Acid -- Titration Curves of a Polyprotic Weak Acid, Weak Base, or Polyampholyte -- Buffer Capacity of a Buffer Solution Containing a Polyprotic Weak Acid or Weak Base and Its Conjugate Base or Acid -- Sparingly Soluble Salts. |
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Solubility Product Constant and Solubility of Sparingly Soluble Salts -- Solubility of Sparingly Soluble Salts of Weak Acids or Weak Bases -- Effect of Ionic Strength on Solubility of Sparingly Soluble Salts -- Solutions and Distribution -- Solutions of Solids and Nonvolatile Liquids in Liquids -- Ideal Solutions -- Nonideal Solutions and the Solubility Parameter -- Intermolecular and Intramolecular Interactions between Molecules -- Prediction of Solubility -- Solubilization of Weak Acids or Weak Bases in Cosolvent Systems -- Dissolution Kinetics of Solids in Liquids -- Solutions of Volatile Liquids in Liquids -- Raoult's Law -- Two-Component Liquid Systems -- Three-Component Liquid Systems -- Solutions of Gases in Liquids (Henry's Law) -- Colligative Properties -- Freezing Point Depression and Boiling Point Elevation -- Osmotic Pressure -- Vapor Pressure Lowering -- Isotonic Solutions -- Freezing Point Method -- NaCl Equivalent Method -- Distribution Law (Partition Coefficient) -- Nondissociated and Nonassociated Systems -- Association of a Solute in One Phase -- Dissociation in Aqueous Phase and Association in Oil Phase -- Distribution and Solubilization of Weak Acids or Weak Bases in Micelles and the Aqueous Phase -- Distribution and Solubilization of Drug Chemicals by Inclusion Complex Formation -- Distribution of Drugs in Proteins (Protein Binding) -- Surface Chemistry and Colloids -- Adsorption from Solutions -- Adsorption Processes -- Adsorption Isotherms -- Langmuir Isotherm -- Freundlich Isotherm -- BET Isotherm. |
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Competitive Adsorption -- Factors Affecting Adsorption -- Nature of the Adsorbent -- Nature of the Adsorbate -- pH -- Temperature -- Liquid-Liquid Systems (Emulsions) -- Liquid-Liquid Interfacial Tension -- Adsorption of Surfactants at Interfaces -- Surfactants and Theory of Emulsification -- Surface-Active Materials -- Naturally Occurring and Semisynthetic Materials -- Finely Divided Solids -- Type of Emulsion and HLB System -- Instability of Emulsions -- Micellization and Solubilization -- Microemulsions -- Solid-Liquid Systems (Suspensions) -- Wetting and Wetting Agents -- Surfactants -- Hydrocolloids -- Solvents -- Electrical Double Layer and Stabilization of Colloidal Particles -- The Electric Double Layer -- The Stabilization and Destabilization of Colloid Systems -- Sedimentation of Dilute Suspensions -- Prevention of Cake Formation -- Kinetics -- Pathways of Drug Degradation -- Hydrolysis -- Oxidation -- Photolysis -- Single and Multiple Reactions, Elementary Reactions, Molecularity, and Order of Reactions -- Irreversible Reactions -- Zero-Order Reactions -- First-Order Reactions -- Apparent Zero-Order Reactions -- Second-Order Reactions -- Determination of the Order of Reaction and Its Rate Constant -- Differentiation Method -- Integration Method -- Other Irreversible Reactions -- Autocatalytic Reactions -- Parallel Reactions -- Consecutive Reactions -- Reversible Reactions -- Reversible First-Order Reactions -- Reversible Second-Order Reactions -- Reversible and Series Reactions (Eigenvalue Method). |
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Use of Laplace Transform for Differential Rate Equations -- Definitions and Properties -- Applications of Laplace Transforms for Drug Degradation and Biotransformation -- Enzyme-Substrate Reactions -- Enzyme-Substrate Reactions without Inhibition -- Enzyme-Substrate Reaction with Inhibition -- Acid-Base Catalyzed Degradation Kinetics -- Acid-Base Catalyzed Hydrolysis of Neutral Chemicals -- Acid-Base Catalyzed Hydrolysis of Polyprotic Weak Acids and Weak Bases -- Oxidation (Free Radical Reaction) -- Degradation Kinetics in Inclusion Complexes, Micelles, and Liposomes -- Temperature Effects on the Reaction Rate Constants -- Diffusion -- Transport Processes -- Diffusion Coefficients -- Diffusion through a Membrane -- Unsteady-State Diffusion through a Membrane -- Steady-State Diffusion through a Membrane -- Constant Activity Reservoir Systems -- Nonconstant Activity Reservoir Systems -- Multilayer Membrane Devices -- Diffusion in a Monolithic Matrix -- Dissolved Drug in Polymeric Drug Carriers -- Dispersed Drug in Polymeric Drug Carriers -- Diffusion in a Membrane-Matrix System -- Diffusion during the Swelling of a Matrix -- Diffusion in Matrix Erosion/Degradation -- Homogeneous Erosion/Degradation -- Heterogeneous Erosion/Degradation -- Diffusion in a Matrix Swelling/Erosion -- Diffusion with Chemical Reaction in a Membrane -- Surface Area and Concentration Gradient Systems -- Osmotically Controlled Systems -- Polymer Science -- Classification of Polymers -- Molecular Weight and Molecular Weight Distribution of Polymers. |
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Characterization of Polymers -- Viscosity Method -- Osmometry -- Light Scattering -- Size Exclusion Chromatography (SEC) -- Effective Linear Calibration Method without Peak Broadening Correction -- Effective Linear Calibration Method with Peak Broadening Correction -- Universal Calibration Method -- Multiple Detector System (e.g., Concentration and Light-Scattering Detectors) -- Polymer Synthesis -- Addition Homo-Polymerization (Free-Radical Homo-Polymerization) -- Polyvinylpyrrolidone (PVP) and Its Copolymers -- Polyvinylacetate and Its Derivatives -- Polyvinylchloride (PVC) -- Polyisobutylene (PIB) -- Free-Radical Copolymerization -- Eudragit and Kollicoat Series -- Ion Exchange Resins -- Carbopol or Carbomer -- Poly(ethylene-co-vinyl acetate) (PEVAc) -- Poly(vinyl alcohol-grafted-ethylene glycol) (Kollicoat, IR) -- Step Polymerization (Condensation Polymerization) -- Acid-Catalyzed Esterification Polymerization of A-A and B-B -- Self-Catalyzed Condensation Polymerization -- Molecular Weight Control -- Polyanhydrides -- Poly(orthoesters) -- Poly(amino acids) -- Silicone Polymers -- Ring-Opening Polymerization -- Polylactic Acid, Polyglycolic Acid, and Polycaprolactone -- Polyethylene Glycol (PEG), Polyethylene Oxide (PEO), and Block Copolymers of Ethylene Oxide and Propylene Oxide (PEOPO) -- Polyphosphazene (PPP) -- Natural Polymers and Their Modification -- Cellulose -- Cellulose Derivatives -- Chitosan -- Polysaccharides -- Gelatin. |
| Subject(s) |
Drugs -- Dosage forms.
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Pharmacy.
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Pharmaceutical technology.
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